Definition - What does Progyluton mean?

Progyluton is an oral combination hormonal medication that is used to regulate menstrual cycles in women who do not menstruate or have irregular cycles. Progyluton is also used to reduce menopausal side effects. Sometimes Progyluton is used to reduce the side effects of polycystic ovary syndrome (PCOS).

Progyluton is a hormone combination pack that consists of low-dose estrogen and progesterone. The doses are so low that it does not prevent ovulation like oral contraceptive hormones do. The hormones supplement estrogen that may be too low in some women which may be causing irregular cycles or menopausal symptoms.

This medication is not available in the USA.

FertilitySmarts explains Progyluton

In PCOS, irregular hormone levels may lead to irregular menstrual cycles or not having periods. Oral contraceptives have been shown to be effective in correcting menstrual irregularities. Progyluton may be an option to do so with lower doses of hormones than oral contraceptives thus producing fewer unwanted side effects. It should be explicitly stated that Progyluton will not prevent ovulation and is not a form of birth control. Progyluton may be beneficial in regulating menstrual cycles prior to preparing to try to become pregnant or prior to undergoing in vitro fertilization (IVF) treatment since ovulation is not disrupted.

There are 11 tablets of low dose estradiol valerate (estrogen) and 10 tablets of low dose estradiol valerate with norgestrel (progesterone) taken sequentially during a women’s menstrual cycle. These are followed by seven days of taking no tablets which is when menstrual bleeding normally occurs.

Common side effects of progluton are similar to oral contraceptives. These include headache, weight change, abdominal pain and nausea, breast tenderness, fluid retention, and irregular or breakthrough vaginal bleeding. Serious but rare effects of using hormone therapy include heart attack, stroke, or blood clotting. These serious effects are unusual in young healthy women. Women who smoke or are advanced in age may have an increased risk of these serious side effects.

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