Definition - What does Medrol mean?

Medrol is a corticosteroid medication that is used for anti-inflammatory purposes after an egg retrieval procedure as part of an in vitro fertilization (IVF) cycle. Its anti-inflammatory (reduction of swelling) and antiproliferative (stopping cell growth) properties are thought to improve the intrauterine environment and aid in endometrial implantation of an embryo.

It is also used in therapy for reducing ovarian hyperstimulation syndrome (OHSS) in high-risk women undergoing IVF. Medrol is also used in both males and females with certain conditions that produce antibodies attributing to infertility.

Medrol may also be known as methylprednisolone.

FertilitySmarts explains Medrol

Medrol reduces the body's signals for inflammation and curbs the immune response. It also lessens blood vessel swelling at sites of injury.

Medrol when used to aid in embryo implantation, is often prescribed once daily starting on the day of in vitro fertilization (IVF) egg retrieval and is taken until the day of embryo transfer.

When used to prevent OHHS it is often prescribed after ovarian stimulation until the first positive pregnancy test (day 13 of an IVF cycle usually).

It is best to take this medication in the morning with food in order to avoid gastrointestinal upset. Common short-term side effects may include increase appetite, fluid retention, insomnia, mood changes, anxiety and limb pain. Patients with a history of hypertension or diabetes should be warned of the potential worsening of these conditions.

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