Zygote Intrafallopian Transfer (ZIFT)

Definition - What does Zygote Intrafallopian Transfer (ZIFT) mean?

Zygote intrafallopian transfer (ZIFT) is an assisted reproductive technology (ART) that involves placing a lab-developed embryo directly into a woman’s fallopian tube. ZIFT is the most invasive ART available and is typically reserved for cases of previous ART treatment failures.

ZIFT is also called tubal embryo transfer (TET).

FertilitySmarts explains Zygote Intrafallopian Transfer (ZIFT)

The early stages of ZIFT are identical to that of in vitro fertilization (IVF). Ovulation induction is utilized to produce a series of eggs. The eggs are retrieved and fertilized in a lab with sperm provided through a semen sample or extraction method. However, instead of waiting the 3-5 days that are standard with IVF, the ZIFT procedure only required 24-hours of development before transferring the embryo into the woman’s body.

The insertion procedure is surgical, requiring a laparoscopic procedure. A minimally invasive incision is made, and the embryo is deposited directly into a woman’s fallopian tube.

ZIFT is not an appropriate procedure for anyone who has the following conditions:

  • Tubal blockage
  • Severe damage in the fallopian tubes
  • Uterine conditions preventing implantation or embryo growth
  • Incapable sperm



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