Intralipid Infusion Therapy

Definition - What does Intralipid Infusion Therapy mean?

Intralipid infusion therapy is a sterile mixture of natural fats including soy oil, chicken egg yolk, and glycerine that is administered intravenously to prevent implantation failure.

Women with recurrent pregnancy loss (RPL) and recurrent implantation failure (RIF) tend to have elevated levels of a subset of white blood cells known as natural killer cells (NK cells). This intralipid mixture acts to "down regulate" these natural killer cells that are thought to attack a developing embryo and prevent its implantation. Intralipids are believed to interfere with the signals in the immune system to stop the attack or rejection of the embryo.


FertilitySmarts explains Intralipid Infusion Therapy

The procedure is considered experimental for the treatment of fertility, but research is promising. A 2011 study involving 96 women - with an average age of 37 - and at least 6 failed IVF attempts saw 50% of the woman who received Intralipid infusions achieving successful pregnancies, compared to nine per cent who were not treated. Two of the women who received the infusion had miscarriages compared to seven miscarriages or 64 per cent, in those not receiving it. Larger randomized studies are needed to prove the theory.

This non-invasive procedure is generally carried out as part of an In vitro fertilization (IVF) or Intrauterine insemination (IUI) treatment cycle. While the infusion has little risk, it is not suitable for women with soy or egg product allergies or a history of high cholesterol or liver disease.

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