Definition - What does Humegon mean?

Humegon is injectable form of human menopausal gonadotropin (hMG). Humegon contains the hormones follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which naturally rise and fall during different times of a woman’s menstrual cycle. FSH stimulates the growth of follicles where egg cells are developed. LH surges to trigger ovulation in women.

Humegon is used to stimulate ovulation (egg release) during infertility treatments and in vitro fertilization (IVF). HMG is sometimes used instead of clomiphene in some fertility regimens or in women who are poor or non-responders to clomiphene therapy.

HMG is also known by the names of Pergonal, Humegon, Menopur, and Repronex. It is sometimes referred to as a menotropin or gonadotropin. The trademark name Humegon may no longer be commercially available in some countries.

FertilitySmarts explains Humegon

HMG is administered by injection intramuscularly (IM) or subcutaneously (under the skin). HMG is administered usually once daily for the first five to twelve days of a treatment cycle during IVF or ovulation induction. It is often used with the medication human chorionic gonadotropin (hCG) to help with ovulation induction.

HMG increases the chance of releasing multiple eggs and multiple pregnancies are more likely (20-40% occurrence rate). Women will be monitored frequently with ultrasounds to assess their ovarian response to this medication. Sometimes blood tests are used to monitor hormone levels.

Common side effects may include injection site irritation which may be avoided by rotating injection sites. Other side effect are nausea, vomiting, abdominal pain, headache, or bloating. Serious side effects include ovarian hyperstimulation syndrome (OHSS) and blood clotting. The patient should report any unusual severe abdominal pain with abdominal swelling to their doctor immediately.

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