Failed IVF Cycle

Definition - What does Failed IVF Cycle mean?

Failed IVF cycle refers to the failure of a cycle of in vitro fertilization (IVF) to result in a successful pregnancy. This occurs when the transferred embryo(s) do not effectively implant in the uterine wall. After a failed IVF cycle, individuals or couples have the option to proceed with another cycle of IVF in hopes that the next cycle will result in a successful pregnancy.

FertilitySmarts explains Failed IVF Cycle

A cycle refers to the entire process of IVF, including ovarian stimulation, egg retrieval, sperm collection, fertilization, transfer, and progesterone therapy. When this does not result in a successful pregnancy, it is known as a failed IVF cycle.

An IVF cycle fails when the embryo(s) transferred to the woman's uterus do not successfully implant. This is due to either a problem with the embryo(s) or the uterus. Fertility experts believe that most cases are due to an arrest embryo's development. This is usually a result of chromosomal abnormalities in the embryo.

After a failed IVF cycle, an individual or couple has the option to undergo another cycle of IVF. Success rates for second cycles of IVF are only slightly lower than first attempts at IVF. There may be some modifications to the procedure to increase the chances of success. If ovarian stimulation did not produce many mature eggs, the drug protocol may be adjusted for the next cycle. If there were significant issues with the egg or embryo quality, it is likely due to a problem with the eggs. Poor lab conditions in the IVF clinic could also result in low-quality embryos. Individuals or couples may opt to try another cycle at a different clinic. If multiple cycles of IVF have failed, donor eggs, donor sperm, or donor embryos may be considered.

A fertility specialist should be able to advise an individual or couple of their chances of becoming pregnant with another cycle of IVF.

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